Examples of how OncoSim has been used

• All cancers
• Breast cancer
• Cervical cancer/HPV
• Colorectal cancer
• Lung cancer
• COVID-19 modelling
• Other

All cancers

• Cancer in Canada – Future Projections
• The Economic Burden of Cancer in Canada from a Societal Perspective
• Cancer burden attributable to risk factors
• Estimates of future cancer mortality attributable to modifiable risk factors in Canada

Breast cancer

• The Value of All-Cause Mortality as a Metric for Assessing Breast Cancer Screening
• The impact of episodic screening interruption: COVID-19 and population-based cancer screening in Canada
• The OncoSim-Breast cancer microsimulation model
• The OncoSim-Breast model reproduces the observed effects of a randomized screening trial
• Potential benefits of reducing breast cancer screening abnormal call rates

Cervical cancer/HPV

• Evaluation of the natural history of cancer of the cervix, implications for prevention. The Cancer Risk Management Model (CRMM) – Human papillomavirus and cervical components
• Using the Cancer Risk Management Model to evaluate the health and economic impacts of cytology compared with human papillomavirus DNA testing for primary cervical cancer screening in Canada
• Exploring the health outcomes of various pan-Canadian cervical cancer screening programs using microsimulation modeling
• Comparing the health and economic impacts of cervical cancer screening strategies using the Cancer Risk Management Model (CRMM)
• Starting cervical cancer screening at 25 years of age: the time has come
• Moving towards the elimination of cervical cancer: modeling the health and economic benefits of increasing HPV vaccine uptake
• Canadian Cancer Statistics, 2016; Special topic: HPV associated cancers
• Action plan for the elimination of cervical cancer

Colorectal cancer

• Prioritisation of colonoscopy services in colorectal cancer screening programmes to minimise impact of COVID-19 pandemic on predicted cancer burden: A comparative modelling study
• The impact of episodic screening interruption: COVID-19 and population-based cancer screening in Canada
• Participatory simulation modeling to inform colorectal cancer screening in a complex remote northern health system: Canada’s Northwest Territories 
• Using the Cancer Risk Management Model to evaluate colorectal cancer screening options for Canada
• Projected Effect of Fecal Immunochemical Test Threshold for Colorectal Cancer Screening on Outcomes and Costs for Canada using the OncoSim Microsimulation Model
• Simulating Results from Trials of Sigmoidoscopy Screening Using the OncoSim Microsimulation Model
• Recommendations on screening for colorectal cancer in primary care
• Family history-based colorectal cancer screening
• Comparing the health and economic impacts of two screening strategies for colorectal cancer in Canada using the Cancer Risk Management Model (CRMM)

Lung cancer

• The evaluation of cancer control interventions in lung cancer using the Canadian Cancer Risk Management Model
• Measuring the population impact of introducing stereotactic ablative radiotherapy for stage I non-small cell lung cancer in Canada
• Eligibility for low-dose computerized tomography screening among asbestos-exposed individuals
• Performance of the cancer risk management model lung cancer screening module
• Cost-effectiveness of lung cancer screening in Canada
• Implementing low-dose computer tomography screening for lung cancer in Canada: implications of alternative at-risk populations, screening frequency and duration
• Biennial lung cancer screening in Canada with smoking cessation—outcomes and cost-effectiveness
• Estimating the cost effectiveness and clinical impact of adding smoking cessation to an organized CT lung cancer screening program in Canada
• Recommendations on screening for lung cancer
• Canadian Cancer Statistics: A 2020 special report on lung cancer
• Canadian Cancer Statistics: A 2018 special report
• Low dose computed tomography for the screening of lung cancer in adults
• Costs and cost-effectiveness of smoking cessation within an organized CT lung cancer screening program.
• How in the real world are lung cancer patients treated?
• Lung cancer-related clinical and economic impacts of achieving a 5% smoking rate by 2035 in Canada
• Comparing the health and economic outcomes of opportunistic lung cancer screening vs. organized lung screening using the Cancer Risk Management Model
• Annual vs. biennial lung cancer screening using the Cancer Risk Management Model to fill gaps in evidence

COVID-19 modelling

• Prioritisation of colonoscopy services in colorectal cancer screening programmes to minimise impact of COVID-19 pandemic on predicted cancer burden: A comparative modelling study
• Impact of the COVID-19 pandemic on FAECAL immunochemical test-based colorectal cancer screening programmes in Australia, Canada, and the Netherlands: A comparative modelling study
• The impact of episodic screening interruption: COVID-19 and population-based cancer screening in Canada

Other

• Canadian Cancer Risk Management Model: Evaluation of cancer control
• The OncoSim Model: Development and use for better decision-making in Canadian cancer control
• Canadian Cancer Statistics, 2015; Special topic: Predictions of the future burden of cancer in Canada
• 2018 Cancer system performance report
• 2017 Cancer system performance report
• Quality and sustainability in cancer control: A system performance report
• Translating research to inform policy decisions